Original Source of Benzyl BenzOate Used in Pharmaceutical Industry
Benzyl benzoate is one of the older preparations used to treat
scabies. Scabies is a skin infection caused by the mite sarcoptes
scabiei. It is characterised by severe itching (particularly at
night), red spots, and may lead to a secondary infection. Benzyl
benzoate is lethal to this mite and so is useful in the treatment
of scabies. It is also used to treat lice infestation of the head
and body. Benzyl benzoate is not the treatment of choice for
scabies due to its irritant properties.
CAS # 120-51-4
EINECS # 204-402-9
Categories Flavor & Fragrance, Organic Intermediates, Personal
Care & Cosmetics, Pharmaceutical & Fine Chemicals, Textile
Used to kill lice and the mites responsible for the skin condition
Mode of Action:
Benzyl benzoate exerts toxic effects on the nervous system of the
parasite, resulting in its death. It is also toxic to mite ova,
though its exact mechanism of action is unknown. In vitro, benzyl
benzoate has been found to kill the Sarcoptes mite within 5
Rapidly hydrolyzed to benzoic acid and benzyl alcohol, which is
further oxidized to benzoic acid. The benzoic acid is conjugated
with glycine to form hippuric acid.
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